{"product_id":"ear2-s40-polyclonal-antibody-bs1925","title":"EAR2 (S40) Polyclonal Antibody-BS1925","description":"\u003cp\u003eEAR2 (S40) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1925-50, BS1925-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P10588\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e \n\n\u003cp\u003eBackground: EAR2 (v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2) protein binds a cis enhancer element (TGACCT motif) upstream of the rennin gene and represses renin gene transcription. EAR2 also contributes to gonadotropin-dependent derepression of LHR promoter activity in granulose cells. EAR2 mRNA is abundant in the liver, and EAR2 protein localizes to the nucleus of As4.1 cells.\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: EAR2 (S40) polyclonal antibody detects endogenous levels of EAR2 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of EAR2 (S40) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: PC12 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: AML-12 whole cell lysate (40ug)\u003cbr\u003e\nLane 3: HEK293T whole cell lysate (40ug)\u003cbr\u003e\nLane 4: HepG2 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of EAR2 (S40) pAb in paraffin-embedded human stomach carcinoma tissue at 1:50.showing Nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 42 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Probable glutamyl-tRNA synthetase; mitochondrial; Glutamate--tRNA ligase; GluRS; EARS2; KIAA1970\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 21-70 of Human EAR2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953216622771,"sku":"BS1925-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953216688307,"sku":"BS1925-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_44f5888c-ae71-4c23-bb43-6d352885d719.jpg?v=1705056949","url":"https:\/\/afsbio.com\/products\/ear2-s40-polyclonal-antibody-bs1925","provider":"AFSBio Inc.","version":"1.0","type":"link"}