{"product_id":"edg-1-polyclonal-antibody-bt-ap02825","title":"EDG-1 Polyclonal Antibody - BT-AP02825","description":"\u003cp\u003eEDG-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02825-20, BT-AP02825-50, BT-AP02825-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Sphingosine-1-phosphate receptor 1 encoded by S1PR1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: S1PR1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: EDG-1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 42696\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P21453; Mouse: O08530; Rat: P48303\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: S1PR1; CHEDG1; EDG1; Sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P1; Endothelial differentiation G-protein coupled receptor 1; Sphingosine 1-phosphate receptor Edg-1; S1P receptor Edg-1; CD\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1901; Mouse: 13609; Rat: 29733\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240275304627,"sku":"BT-AP02825-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240275337395,"sku":"BT-AP02825-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240275370163,"sku":"BT-AP02825-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d075d9e2-0ce6-4199-b94b-f01f92b257be.png?v=1769406089","url":"https:\/\/afsbio.com\/products\/edg-1-polyclonal-antibody-bt-ap02825","provider":"AFSBio Inc.","version":"1.0","type":"link"}