{"product_id":"edn1-monoclonal-antibody-bt-mca2424","title":"EDN1 Monoclonal Antibody - BT-MCA2424","description":"\u003cp\u003eEDN1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2424-50, BT-MCA2424-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin\/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: EDN1\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4E6E5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: EDN1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 24.4KDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P05305\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ET1, QME, PPET1, ARCND3, HDLCQ7\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1906\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238517530803,"sku":"BT-MCA2424-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238517563571,"sku":"BT-MCA2424-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_14efd1ad-a98d-428a-ba7c-7e0e37502836.png?v=1769382030","url":"https:\/\/afsbio.com\/products\/edn1-monoclonal-antibody-bt-mca2424","provider":"AFSBio Inc.","version":"1.0","type":"link"}