{"product_id":"egfr-phospho-y1173-polyclonal-antibody-bs4741","title":"EGFR (phospho-Y1173) Polyclonal Antibody - BS4741","description":"\u003cp\u003eEGFR (phospho-Y1173) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS4741-50, BS4741-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregμlin, betacellμlin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor resμlts in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecμles and lysosomal degradation.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\/ICC, IP\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: EGFR, ERBB, ERBB1, HER1, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y1173 of human EGFR protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500-1:1000\u003cbr\u003e\nIHC: 1:50-1:100\u003cbr\u003e\nIF\/ICC: 1:50-1:100\u003cbr\u003e\nIP: 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: EGFR (phospho-Y1173) polyclonal antibody detects endogenous levels of EGFR protein only when phosphorylated at Tyr1173.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 160 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: ErbB HER Signaling,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P00533\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946312097971,"sku":"BS4741-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946312130739,"sku":"BS4741-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/egfr-phospho-y1173-polyclonal-antibody-bs4741","provider":"AFSBio Inc.","version":"1.0","type":"link"}