{"product_id":"eif2α-phospho-ser51-rabbit-pab-es1304","title":"eIF2α (phospho Ser51) rabbit pAb - ES1304","description":"\u003cp\u003eeIF2α (phospho Ser51) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1304-50, ES1304-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: EIF2S1; EIF2A; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF; WB; IHC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF: 1:50-200 Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat; Dog; Pig; Fish\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Ser51. AA range:21-70\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 38kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1965\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P05198\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, Stress granule. Colocalizes with NANOS3 in the stress granules.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202006442163,"sku":"ES1304-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202006474931,"sku":"ES1304-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_9cdeea8d-7adc-466b-bb1a-e2f95874821c.png?v=1767119801","url":"https:\/\/afsbio.com\/products\/eif2%ce%b1-phospho-ser51-rabbit-pab-es1304","provider":"AFSBio Inc.","version":"1.0","type":"link"}