{"product_id":"eif4a1-mouse-mab-em1136","title":"eIF4A1 Mouse mAb - EM1136","description":"\u003cp\u003eeIF4A1 Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1136-50, EM1136-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA – this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: DDX2, eIF 4A I, Eukaryotic initiation factor 4A-1, ATP-dependent RNA helicase eIF4A-1, DDX2A\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1, 000-3, 000 IF 1:100-200  IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 48kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1973\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P60842\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytosol, Extracellular region or secreted\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201989992627,"sku":"EM1136-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201990025395,"sku":"EM1136-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_7a1e59b2-0667-4ec8-a2d4-a5a42a8fe330.png?v=1767119458","url":"https:\/\/afsbio.com\/products\/eif4a1-mouse-mab-em1136","provider":"AFSBio Inc.","version":"1.0","type":"link"}