{"product_id":"eif4b-phospho-ser422-rabbit-pab-es5967","title":"eIF4B (phospho Ser422) rabbit pAb - ES5967","description":"\u003cp\u003eeIF4B (phospho Ser422) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5967-50, ES5967-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F., similarity:Contains 1 RRM (RNA recognition motif) domain., subunit:Self-associates and interacts with EIF3 p170 subunit.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422. AA range:388-437\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 80kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3716\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P23588\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: cytosol, polysome, eukaryotic translation initiation factor 4F complex, dendrite, neuronal cell body,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202276024499,"sku":"ES5967-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202276057267,"sku":"ES5967-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_03be78a3-22be-4828-a10e-b5e1b0a7d956.png?v=1767125565","url":"https:\/\/afsbio.com\/products\/eif4b-phospho-ser422-rabbit-pab-es5967","provider":"AFSBio Inc.","version":"1.0","type":"link"}