{"product_id":"eif4b-polyclonal-antibody-bs7572","title":"EIF4B Polyclonal Antibody-BS7572","description":"\u003cp\u003eEIF4B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7572-50, BS7572-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P23588\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000\u003cbr\u003e\nIHC\t1:50 - 1:200\u003cbr\u003e\nIF\t1:50 - 1:100\u003cbr\u003e\nIP\t1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Eukaryotic initiation factor 4B (eIF4B) is thought to assist the eIF4F complex in translation initiation. In plants, eIF4B is known to interact with the poly-(A) binding protein, increasing its poly-(A) binding activity. Heat shock and serum starvation cause dephosphorylation of eIF4B at multiple sites with kinetics similar to those of the corresponding inhibition of translation, while phosphorylation of eIF4B following insulin treatment correlates well with an observed increase in translation.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: EIF4B polyclonal antibody detects endogenous levels of EIF4B protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 80 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of EIF4B polyclonal antibody, Immunohistochemistry (IHC) analysis of EIF4B polyclonal antibody in paraffin-embedded Human Breast Cancer tissue., Immunofluorescence analysis of U2OS cells, using EIF4B polyclonal antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Eukaryotic translation initiation factor 4B; eIF-4B; EIF4B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human EIF4B.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42997576433843,"sku":"BS7572-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42997576466611,"sku":"BS7572-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_aed8a39c-b85f-4ee5-97b1-e0da6f85998e.jpg?v=1706270606","url":"https:\/\/afsbio.com\/products\/eif4b-polyclonal-antibody-bs7572","provider":"AFSBio Inc.","version":"1.0","type":"link"}