{"product_id":"eif4ebp1-polyclonal-antibody-e-ab-40327","title":"EIF4EBP1 Polyclonal Antibody - E-AB-40327","description":"\u003cp\u003eEIF4EBP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-40327-60, E-AB-40327-120, E-AB-40327-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: EIF4EBP1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 4E-BP1; 4EBP1; 4EBP1; BP 1; eIF4E binding protein 1; eIF4E-binding protein 1; Eif4ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; PHASI; Phosphorylated heat- and acid-stable protein regulated by insulin 1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q13541\u003c\/p\u003e\n\n\u003cp\u003eBackground: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 1 protein\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:100-1:400\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133436395699,"sku":"E-AB-40327-60","price":175.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133436428467,"sku":"E-AB-40327-120","price":322.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133436461235,"sku":"E-AB-40327-200","price":532.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b43743df-3dc6-4935-9fd4-54c1d105e9c2.png?v=1709899002","url":"https:\/\/afsbio.com\/products\/eif4ebp1-polyclonal-antibody-e-ab-40327","provider":"AFSBio Inc.","version":"1.0","type":"link"}