{"product_id":"eif4g-phospho-ser1108-rabbit-polyclonal-antibody-ra24495","title":"eIF4G (phospho-Ser1108) Rabbit Polyclonal Antibody - RA24495","description":"eIF4G (phospho-Ser1108) Rabbit Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA24495-50, RA24495-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) Homo sapiens The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly (A) -binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:1000-2000\n\nAlternative Names: Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) \n\nApplications: WB\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 1981\n\nProtein MW (KDa): 180\n\nSWISS: Q04637\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121254654131,"sku":"RA24495-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121254686899,"sku":"RA24495-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5f4ff431-3dde-46f2-b479-1cc6f6ad4d60.png?v=1773345754","url":"https:\/\/afsbio.com\/products\/eif4g-phospho-ser1108-rabbit-polyclonal-antibody-ra24495","provider":"AFSBio Inc.","version":"1.0","type":"link"}