{"product_id":"eif4g-polyclonal-antibody-ra24496","title":"eIF4G Polyclonal Antibody - RA24496","description":"eIF4G Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA24496-50, RA24496-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) Homo sapiens The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly (A) -binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:500-2000 Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/5000. Not yet tested in other applications.\n\nAlternative Names: EIF4G1; EIF4F; EIF4G; EIF4GI; Eukaryotic translation initiation factor 4 gamma 1; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220\n\nApplications: IHC-p; IF\/ICC; WB; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 1981\n\nProtein MW (KDa): 175\n\nSWISS: Q04637\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121254752435,"sku":"RA24496-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121254785203,"sku":"RA24496-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_59fec35b-fca4-4b02-8d4b-8c6043a03442.png?v=1773345755","url":"https:\/\/afsbio.com\/products\/eif4g-polyclonal-antibody-ra24496","provider":"AFSBio Inc.","version":"1.0","type":"link"}