{"product_id":"eif4g3-polyclonal-antibody-e-ab-90908","title":"EIF4G3 Polyclonal Antibody - E-AB-90908","description":"\u003cp\u003eEIF4G3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-90908-60, E-AB-90908-120, E-AB-90908-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: EIF4G3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: EIF4G3; eIF-4G 3; eIF4G 3; eIF4GII; eIF-4G3; eIF4G3\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O43432\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human EIF4G3\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 55kDa\/146kDa\/176kDa\/177kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 250kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148761071795,"sku":"E-AB-90908-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148761104563,"sku":"E-AB-90908-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148761137331,"sku":"E-AB-90908-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a28990ea-529b-4173-ab45-31a7ee277ce4.png?v=1710329456","url":"https:\/\/afsbio.com\/products\/eif4g3-polyclonal-antibody-e-ab-90908","provider":"AFSBio Inc.","version":"1.0","type":"link"}