Human leukocyte elastase
HLE
Elastase 2
Size: 1.0mg
Source: Human Neutrophils
Catalogue Number: ATE01-10
Product Information
Elastase datasheetClinical Indications
Primary Sclerosing Cholangitis
Crohn's disease
Ulcerative Colitis
Systemic Lupus Erythematosus
Elastase is implicated in congenital and cyclic neutropenia
MSDS
References
Baugh, R.J., Travis, J. (1976) Human leukocyte elastase: rapid isolation and characterization. Biochemistry 15, 836-41
Navia, M.A. et al. (1989) Structure if human neutrophil elastase in complex with peptide chloromethyl ketone inhibitor at 84-A resolution. Proc. Natl. Acad. Sci. USA 86, 7-11
Sato, T. et al. (2006) Neutrophil elastase and cancer. Surg. Oncol. 15, 217-22
Ho, A.-S. et al. (2014) Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers. Oncotarget 5, 473-80
Philip, A.G. et al. (1994) Neutrophil elastase in the diagnosis of neonatal infection.
Pediatr. Infect. Dis. J. 4, 323-6
Zorn, B. et al. (2003) Semen polymorphonuclear neutrophil elastase as a diagnostic and prognostic marker or genital tract inflammation - a review. Clin. Chem. Lab. Med. 41, 2-12
Langhorst, J. et al. Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP and clinical indices. Am. J. Gastroenterol. 103, 162-9
Cohen Tervaert, J.W. et al. (1993) Occurrence of autoantibodies to human leucocyte elastase in Wegener's granulomatosis and other inflammatory bowel disorders. Ann. Rheum. Dis. 52, 115-20
Dale, D.C. et al. (2000) Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia. Blood 96, 2317-22