{"product_id":"endonuclease-g-polyclonal-antibody-cas75127","title":"Endonuclease G Polyclonal Antibody-CAS75127","description":"\u003cp\u003eEndonuclease G Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: CAS75127-50, CAS75127-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot:  Q14249\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IP,  IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:2000~1:5000\u003cbr\u003e\nIP:1:2000~8000\u003cbr\u003e\nIHC:1:50~1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: Endonuclease G (EndoG) is a nuclear-encoded mitochondrial nuclease that has been reported to function in apoptosis, DNA recombination and cell proliferation. EndoG is expressed as a precursor protein containing an amino-terminal mitochondrial targeting sequence which is removed when the protein is imported into the mitochondria. During apoptosis EndoG is released from the mitochondria, translocates to the nucleus and cooperates with other nucleases to trigger DNA fragmentation associated with the apoptotic process\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Endonuclease  G polyclonal antibody detects endogenous levels of Endonuclease  G protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 30 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Endonuclease G polyclonal antibody at 1:5000 dilution\u003cbr\u003e\n Lane 1: K562 whole cell lysate (40ug)\u003cbr\u003e\n Lane 2: U-87MG whole cell lysate (40ug)\u003cbr\u003e\n Lane 3: HepG2 whole cell lysate (40ug)\u003cbr\u003e\n Lane 4: The Heart tissue lysate of Mouse (40ug)\u003cbr\u003e\n Lane 5: The Muscle tissue lysate of RAT (40ug), Immunoprecipitation - Endonuclease G Polyclonal Antibody, Immunohistochemistry of paraffin-embedded human colon carcinoma using Endonuclease G antibody at dilution of 1:50., Immunohistochemistry of paraffin-embedded human colon carcinoma using Endonuclease G antibody at dilution of 1:50.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Endonuclease G, mitochondrial ; Endo G; ENDOG\u003c\/p\u003e\n\n\n\u003cp\u003eImmunogen: Recombinant protein of human Endonuclease G.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43058777096371,"sku":"CAS75127-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43058777129139,"sku":"CAS75127-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_118d0fe0-91f1-4e57-b2f3-657e7fbf4cb2.jpg?v=1708172183","url":"https:\/\/afsbio.com\/products\/endonuclease-g-polyclonal-antibody-cas75127","provider":"AFSBio Inc.","version":"1.0","type":"link"}