{"product_id":"endothelin-b-receptor-polyclonal-antibody-ra24566","title":"Endothelin B Receptor Polyclonal Antibody - RA24566","description":"\u003cp\u003eEndothelin B Receptor Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA24566-50, RA24566-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: endothelin receptor type B (EDNRB) Homo sapiens The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Endothelin B receptor (ET-B;ET-BR;Endothelin receptor non-selective type) ; YM3547\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p; IF (paraffin section)\u003c\/p\u003e \n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 1910\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 50\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P24530\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121257963699,"sku":"RA24566-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121257996467,"sku":"RA24566-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3d3ce356-273a-43b0-93f6-cda9992da2aa.png?v=1773345781","url":"https:\/\/afsbio.com\/products\/endothelin-b-receptor-polyclonal-antibody-ra24566","provider":"AFSBio Inc.","version":"1.0","type":"link"}