{"product_id":"ephrin-a5-p63-polyclonal-antibody-bs2478","title":"Ephrin-A5 (P63) Polyclonal Antibody-BS2478","description":"\u003cp\u003eEphrin-A5 (P63) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2478-50, BS2478-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P52803\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e \n\n\u003cp\u003eBackground: Ephrin A5, a member of the ephrin family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Ephrin-A5 (P63) polyclonal antibody detects endogenous levels of Ephrin-A5 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Ephrin-A5 (P63) polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane 1: A549 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: MCF-7 whole cell lysate (40ug)\u003cbr\u003e\nLane 3: CT26 whole cell lysate (40ug)\u003cbr\u003e\nLane 4: H9C2 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of Ephrin-A5 (P63) pAb in paraffin-embedded human brain tissue.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 25 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Ephrin A5; AL-1; AL1; EPH-related receptor tyrosine kinase ligand 7; LERK-7; EFNA5; EPLG7; LERK7\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 50-100 of Human Ephrin-A5.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953226322099,"sku":"BS2478-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953226354867,"sku":"BS2478-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f0a6145b-f3cc-40a9-b0b1-df075dc9f9fa.jpg?v=1705057168","url":"https:\/\/afsbio.com\/products\/ephrin-a5-p63-polyclonal-antibody-bs2478","provider":"AFSBio Inc.","version":"1.0","type":"link"}