{"product_id":"ercc2-polyclonal-antibody-e-ab-65037","title":"ERCC2 Polyclonal Antibody - E-AB-65037","description":"\u003cp\u003eERCC2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-65037-60, E-AB-65037-120, E-AB-65037-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ERCC2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ERCC2; COFS2; EM9; TFIIH; TTD; TTD1; XPD\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P18074\u003c\/p\u003e\n\n\u003cp\u003eBackground: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2\/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3\/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human ERCC2 (NP_001124339.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46kDa\/86kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 80kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146358259891,"sku":"E-AB-65037-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146358292659,"sku":"E-AB-65037-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146358325427,"sku":"E-AB-65037-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3c9e8a0d-3111-4268-9b13-5e80c2e61d97.png?v=1710294193","url":"https:\/\/afsbio.com\/products\/ercc2-polyclonal-antibody-e-ab-65037","provider":"AFSBio Inc.","version":"1.0","type":"link"}