{"product_id":"ercc3-rabbit-pab-a12702","title":"ERCC3 Rabbit pAb - A12702","description":"\u003cp\u003eERCC3 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A12702-20, A12702-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 89kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 89kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2071\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P19447\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: XPB; BTF2; Ssl2; TTD2; GTF2H; RAD25; TFIIH; ERCC3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Transcription Factors, DNA Damage Repair, Cancer, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Nucleotide metabolism.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: ERCC3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189533794483,"sku":"A12702-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189533827251,"sku":"A12702-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_c5509bea-2b7f-4018-bd3a-ef4527ae84f4.png?v=1766429226","url":"https:\/\/afsbio.com\/products\/ercc3-rabbit-pab-a12702","provider":"AFSBio Inc.","version":"1.0","type":"link"}