{"product_id":"erg-kcnh2-polyclonal-antibody-bs65805","title":"ERG\/KCNH2 Polyclonal Antibody-BS65805","description":"ERG\/KCNH2 Polyclonal Antibody\n\nSizes: 50µl, 100µl\n\nCatalogue Numbers: BS65805-50, BS65805-100\n\nProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\n\nSwiss-Prot: Q12809\n\nHost: Rabbit\n\nReactivity: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,\n\nApplications: ICC,\n\nAll Applications: ICC=1:100-500\n\nBackground: The potassium voltage gated channel, subfamily H (eag related), member 2 (KCNH2) gene encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in KCNH2 have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. KCNH2 channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.Highly expressed in heart and brain.\n\nPurification and Purity: affinity purified by Protein A\n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles.\n\nSpecificity: ERG\/KCNH2  Polyclonal Antibody detects endogenous levels of ERG\/KCNH2 protein.\n\nBioworld Molecular Weight: ~127 kDa\n\nNote: For research use only, not for use in diagnostic procedure.\n\nExtra Notes: Tissue\/cell: MCF-7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min;Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (ERG\/KCNH2) Polyclonal Antibody, Unconjugated 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (5ug\/ml, blue, C-0033) was used to stain the cell nuclei.\n\nAlternative Name: ERG; ERG1; H ERG; HERG 1; HERG; HERG1; LQT 2; LQT2; Potassium channel HERG; SQT1; Voltagegated potassium channel, subfamily H, member 2; KCNH2_HUMAN.\n\nImmunogen: KLH conjugated synthetic peptide derived from human HERG:1001-1159\/1159\u003ccytoplasmic\u003e\n\nConjugate: Unconjugated\n\nModification: Unmodified\u003c\/cytoplasmic\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43029553086643,"sku":"BS65805-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43029553119411,"sku":"BS65805-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e1405939-a97b-4f85-b9e8-e05e6724b04a.jpg?v=1707221646","url":"https:\/\/afsbio.com\/products\/erg-kcnh2-polyclonal-antibody-bs65805","provider":"AFSBio Inc.","version":"1.0","type":"link"}