{"product_id":"erln2-rabbit-pab-es16681","title":"ERLN2 rabbit pAb - ES16681","description":"\u003cp\u003eERLN2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES16681-50, ES16681-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1, 4, 5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012],\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1: 500-2000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human ERLN2 AA range: 239-289\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 11160\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O94905\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Associated with lipid raft-like domains of the endoplasmic reticulum membrane.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201650483379,"sku":"ES16681-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201650516147,"sku":"ES16681-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_99b76cf8-9e3f-4c19-8a55-63d7f9d9dc4e.png?v=1767108531","url":"https:\/\/afsbio.com\/products\/erln2-rabbit-pab-es16681","provider":"AFSBio Inc.","version":"1.0","type":"link"}