{"product_id":"err3-polyclonal-antibody-bt-ap08984","title":"ERR3 Polyclonal Antibody - BT-AP08984","description":"\u003cp\u003eERR3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08984-20, BT-AP08984-50, BT-AP08984-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expre\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Epigenetics and nuclear signaling; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ESRRG\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Estrogen-related receptor gamma\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P62508; Mouse: P62509; Rat: P62510\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Estrogen-related receptor gamma;ERR gamma-2;Estrogen receptor-related protein 3;Nuclear receptor subfamily 3 group B member 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2104\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239133929651,"sku":"BT-AP08984-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239133962419,"sku":"BT-AP08984-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239133995187,"sku":"BT-AP08984-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cca5cceb-7fbc-4d22-adb4-542fa7168060.png?v=1769389592","url":"https:\/\/afsbio.com\/products\/err3-polyclonal-antibody-bt-ap08984","provider":"AFSBio Inc.","version":"1.0","type":"link"}