{"product_id":"esr1-monoclonal-antibody-bt-mca3942","title":"ESR1 Monoclonal Antibody - BT-MCA3942","description":"\u003cp\u003eESR1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3942-50, BT-MCA3942-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ESR1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 6B6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ESR1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human ESR1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 66kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P03372\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ESR1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2099\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238609281203,"sku":"BT-MCA3942-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238609313971,"sku":"BT-MCA3942-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c092eb51-ae57-4a8f-9af7-802e11948a79.png?v=1769383037","url":"https:\/\/afsbio.com\/products\/esr1-monoclonal-antibody-bt-mca3942","provider":"AFSBio Inc.","version":"1.0","type":"link"}