{"product_id":"et-1-polyclonal-antibody-bt-ap03091","title":"ET-1 Polyclonal Antibody - BT-AP03091","description":"\u003cp\u003eET-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03091-20, BT-AP03091-50, BT-AP03091-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: EDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin\/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: EDN1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ET-1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 24425\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P05305; Mouse: P22387\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: EDN1; Endothelin-1; Preproendothelin-1; PPET1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1906\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240297029811,"sku":"BT-AP03091-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240297062579,"sku":"BT-AP03091-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240297095347,"sku":"BT-AP03091-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4b3f4677-edca-49a9-b909-0828fbe9bac7.png?v=1769406404","url":"https:\/\/afsbio.com\/products\/et-1-polyclonal-antibody-bt-ap03091","provider":"AFSBio Inc.","version":"1.0","type":"link"}