{"product_id":"et-1-rabbit-pab-es3877","title":"ET-1 rabbit pAb - ES3877","description":"\u003cp\u003eET-1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3877-50, ES3877-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin\/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: EDN1; Endothelin-1; Preproendothelin-1; PPET1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC-p: 100-300.Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 25kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1906\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P05305\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202160976051,"sku":"ES3877-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202161008819,"sku":"ES3877-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_2f520cf8-375c-4ebd-afaf-40842ac8ef75.png?v=1767123313","url":"https:\/\/afsbio.com\/products\/et-1-rabbit-pab-es3877","provider":"AFSBio Inc.","version":"1.0","type":"link"}