{"product_id":"etbr-polyclonal-antibody-bt-ap03095","title":"ETBR Polyclonal Antibody - BT-AP03095","description":"\u003cp\u003eETBR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03095-20, BT-AP03095-50, BT-AP03095-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by EDNRB (endothelin receptor type B) is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for EDNRB.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ETBR\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ETBR Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 49644\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P24530; Mouse: P48302\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Endothelin B receptor (ET-B) (ET-BR) (Endothelin receptor non-selective type)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1910; Mouse: 13618\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240297455795,"sku":"BT-AP03095-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240297488563,"sku":"BT-AP03095-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240297521331,"sku":"BT-AP03095-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_934e3754-2301-4aaf-b0f2-10068cbdaf93.png?v=1769406409","url":"https:\/\/afsbio.com\/products\/etbr-polyclonal-antibody-bt-ap03095","provider":"AFSBio Inc.","version":"1.0","type":"link"}