{"product_id":"eto-2-polyclonal-antibody-bt-ap03098","title":"ETO-2 Polyclonal Antibody - BT-AP03098","description":"\u003cp\u003eETO-2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03098-20, BT-AP03098-50, BT-AP03098-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CBFA2T3 (CBFA2\/RUNX1 translocation partner 3) encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t (16; 21) (q24; q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of CBFA2T3. CBFA2T3 is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CBFA2T3\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ETO-2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 71192\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O75081; Mouse: O54972\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CBFA2T3; MTG16; MTGR2; ZMYND4; Protein CBFA2T3; MTG8-related protein 2; Myeloid translocation gene on chromosome 16 protein; hMTG16; Zinc finger MYND domain-containing protein 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 863; Mouse: 12398\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240297750707,"sku":"BT-AP03098-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240297783475,"sku":"BT-AP03098-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240297816243,"sku":"BT-AP03098-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_804a6de1-f026-4957-ac92-c3b94474a7a6.png?v=1769406413","url":"https:\/\/afsbio.com\/products\/eto-2-polyclonal-antibody-bt-ap03098","provider":"AFSBio Inc.","version":"1.0","type":"link"}