{"product_id":"eya3-polyclonal-antibody-e-ab-66408","title":"EYA3 Polyclonal Antibody - E-AB-66408","description":"\u003cp\u003eEYA3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-66408-60, E-AB-66408-120, E-AB-66408-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: EYA3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: EYA3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q99504\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human EYA3 (NP_001981.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IF \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 48kDa\/56kDa\/57kDa\/58kDa\/62kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 57kDa\/58kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146415440051,"sku":"E-AB-66408-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146415472819,"sku":"E-AB-66408-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146415505587,"sku":"E-AB-66408-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_36dc44d2-2fc7-440f-8d50-24bac4aef3cf.png?v=1710295185","url":"https:\/\/afsbio.com\/products\/eya3-polyclonal-antibody-e-ab-66408","provider":"AFSBio Inc.","version":"1.0","type":"link"}