{"product_id":"factor-viii-polyclonal-antibody-bz16436","title":"Factor VIII Polyclonal Antibody-BZ16436","description":"\u003cp\u003eFactor VIII Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16436-50, BZ16436-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P00451\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eFactor VIII Polyclonal Antibody-BZ16436\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000 IHC: 1\/50-1\/100 ELISA: 1\/10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: F8: coagulation factor VIII, procoagulant component. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 267 kDa; Observed MW: 300 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Factor VIII in HuvEcLysates using Factor VIII antibody., Western blot analysis of Factor VIII in HuvEcLysates using Factor VIII antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: F8; F8C; Coagulation factor VIII; Antihemophilic factor; AHF; Procoagulant component\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from the C-terminal region of human Factor VIII. at AA rangle: 2130-2210\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957312393395,"sku":"BZ16436-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957312426163,"sku":"BZ16436-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_29ceae56-421e-4657-8876-49bfd14b270d.jpg?v=1705144721","url":"https:\/\/afsbio.com\/products\/factor-viii-polyclonal-antibody-bz16436","provider":"AFSBio Inc.","version":"1.0","type":"link"}