{"product_id":"fam48a-rabbit-pab-es8546","title":"FAM48A rabbit pAb - ES8546","description":"\u003cp\u003eFAM48A rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8546-50, ES8546-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and\/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail., similarity:Belongs to the FAM48 family., subunit:Interacts with MAPK14., tissue specificity:Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: FAM48A C13orf19 FP757\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 85kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 55578\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q8NEM7\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202386387123,"sku":"ES8546-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202386419891,"sku":"ES8546-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_5fc416f3-2be3-4f94-a096-e200204015d6.png?v=1767128015","url":"https:\/\/afsbio.com\/products\/fam48a-rabbit-pab-es8546","provider":"AFSBio Inc.","version":"1.0","type":"link"}