{"product_id":"fas-l-polyclonal-antibody-ra20836","title":"FAS-L Polyclonal Antibody - RA20836","description":"\u003cp\u003eFAS-L Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA20836-50, RA20836-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Fas ligand (FASLG) Homo sapiens This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS\/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE) . Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: FASLG; APT1LG1; CD95L; FASL; TNFSF6; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD antigen CD178\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 356\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 33\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P48023\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120696877235,"sku":"RA20836-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120696910003,"sku":"RA20836-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f273dacb-dbde-45e1-9dc8-4a472e6d0f33.png?v=1773369684","url":"https:\/\/afsbio.com\/products\/fas-l-polyclonal-antibody-ra20836","provider":"AFSBio Inc.","version":"1.0","type":"link"}