{"product_id":"fas-l-polyclonal-antibody-ra24881","title":"FAS-L Polyclonal Antibody - RA24881","description":"\u003cp\u003eFAS-L Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA24881-50, RA24881-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Fas ligand (FASLG) Homo sapiens This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS\/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE) . Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand;APTL;CD95 ligand;CD95-L;Fas antigen ligand;Fas ligand;FasL;CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain;Soluble Fas ligand;sFasL) ; ADAM10-processed FasL form (APL) ; FasL intracellular domain (FasL ICD;SPPL2A-processed FasL form;SPA) ]\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 356\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P48023\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120299303091,"sku":"RA24881-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120299335859,"sku":"RA24881-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e028ce96-d3c0-412f-b0db-ee902c88f4df.png?v=1773356811","url":"https:\/\/afsbio.com\/products\/fas-l-polyclonal-antibody-ra24881","provider":"AFSBio Inc.","version":"1.0","type":"link"}