{"product_id":"fascin-1-polyclonal-antibody-ra24880","title":"Fascin 1 Polyclonal Antibody - RA24880","description":"Fascin 1 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA24880-50, RA24880-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: fascin actin-bundling protein 1 (FSCN1) Homo sapiens This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-300 ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: FSCN1; FAN1; HSN; SNL; Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 6624\n\nProtein MW (KDa): 55\n\nSWISS: Q16658\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121274282163,"sku":"RA24880-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121274314931,"sku":"RA24880-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2afa7f13-6ffa-446f-a3a2-e2c3c2454b45.png?v=1773345916","url":"https:\/\/afsbio.com\/products\/fascin-1-polyclonal-antibody-ra24880","provider":"AFSBio Inc.","version":"1.0","type":"link"}