{"product_id":"fat1-polyclonal-antibody-bt-ap15536","title":"FAT1 Polyclonal Antibody - BT-AP15536","description":"\u003cp\u003eFAT1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15536-20, BT-AP15536-50, BT-AP15536-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and\/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and\/or alternative promoter usage exist, but they have not been fully described.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Epigenetics and nuclear signaling; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: FAT1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Protocadherin Fat 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q14517\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Protocadherin Fat 1;Cadherin family member 7;Cadherin-related tumor suppressor homolog;Protein fat homolog [Cleaved into: Protocadherin Fat 1, nuclear form]\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2195\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239136780467,"sku":"BT-AP15536-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239136813235,"sku":"BT-AP15536-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239136846003,"sku":"BT-AP15536-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fe145b00-9597-4233-8a7d-4af65d0f7793.png?v=1769389639","url":"https:\/\/afsbio.com\/products\/fat1-polyclonal-antibody-bt-ap15536","provider":"AFSBio Inc.","version":"1.0","type":"link"}