{"product_id":"fat1-polyclonal-antibody-e-ab-13237","title":"FAT1 Polyclonal Antibody - E-AB-13237","description":"\u003cp\u003eFAT1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-13237-60, E-AB-13237-120, E-AB-13237-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: FAT1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Cadherin family member 7; Cadherin family member 7 precursor; Cadherin ME5; Cadherin related tumor suppressor; Cadherin related tumor suppressor homolog; Cadherin related tumor suppressor homolog precursor; Cadherin related tumor suppressor homolog precursor (FAT protein homolog); Cadherin-related tumor suppressor homolog; CDHF 7; CDHF7; FAT 1; FAT tumor suppressor 1; FAT tumor suppressor homolog 1; FAT1; FAT1; hFat 1; hFAT; hFat1; Homolog of Drosophila FAT protein; Homolog of Drosophila FAT protein precursor; Homolog of Drosophila tumor suppressor FAT precursor; ME 5; ME5; nuclear form; Protein fat homolog; Protocadherin Fat 1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q14517\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and\/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and\/or alternative promoter usage exist, but they have not been fully described.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human FAT1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124118323379,"sku":"E-AB-13237-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124118356147,"sku":"E-AB-13237-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124118388915,"sku":"E-AB-13237-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1d478237-9f4c-4379-b17e-21a5e6e58656.png?v=1709724243","url":"https:\/\/afsbio.com\/products\/fat1-polyclonal-antibody-e-ab-13237","provider":"AFSBio Inc.","version":"1.0","type":"link"}