{"product_id":"fbln5-monoclonal-antibody-bt-mca2065","title":"FBLN5 Monoclonal Antibody - BT-MCA2065","description":"\u003cp\u003eFBLN5 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2065-50, BT-MCA2065-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: FBLN5\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1G6A4\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: FBLN5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9UBX5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: EVEC, UP50, ARMD3, DANCE\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10516\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238371319987,"sku":"BT-MCA2065-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238371352755,"sku":"BT-MCA2065-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_04c51df5-ab8a-4557-b4c4-6c6792127918.png?v=1769379347","url":"https:\/\/afsbio.com\/products\/fbln5-monoclonal-antibody-bt-mca2065","provider":"AFSBio Inc.","version":"1.0","type":"link"}