{"product_id":"fbx32-fbox32-polyclonal-antibody-e-ab-93393","title":"Fbx32\/FBOX32 Polyclonal Antibody - E-AB-93393","description":"\u003cp\u003eFbx32\/FBOX32 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93393-60, E-AB-93393-120, E-AB-93393-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Fbx32\/FBOX32\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: FBXO32; Fbx32; MAFbx\u003c\/p\u003e\n\n \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q969P5\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human Fbx32\/FBOX32\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 30kDa\/41kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43145993257139,"sku":"E-AB-93393-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43145993289907,"sku":"E-AB-93393-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43145993322675,"sku":"E-AB-93393-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_03fc2e82-c78e-42f3-a9da-131be422e19f.png?v=1710289435","url":"https:\/\/afsbio.com\/products\/fbx32-fbox32-polyclonal-antibody-e-ab-93393","provider":"AFSBio Inc.","version":"1.0","type":"link"}