{"product_id":"fbxo8-polyclonal-antibody-e-ab-53145","title":"FBXO8 Polyclonal Antibody - E-AB-53145","description":"\u003cp\u003eFBXO8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-53145-60, E-AB-53145-120, E-AB-53145-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: FBXO8\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: DC10; F box only protein 8; F box protein 8; F box protein Fbx8; F box\/SEC7 protein FBS ; F-box only protein 8; F-box\/SEC7 protein FBS; FBS; FBX8; FBX8; FBXO 8; Fbxo8\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9NRD0\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.72 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human FBXO8\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133568549043,"sku":"E-AB-53145-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133568581811,"sku":"E-AB-53145-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133568614579,"sku":"E-AB-53145-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d4f71b2d-e5e6-4c49-b402-a84f1eff8d88.png?v=1709900233","url":"https:\/\/afsbio.com\/products\/fbxo8-polyclonal-antibody-e-ab-53145","provider":"AFSBio Inc.","version":"1.0","type":"link"}