{"product_id":"fbxw5-rabbit-polyclonal-antibody-bt-ap10013","title":"FBXW5 Rabbit Polyclonal Antibody - BT-AP10013","description":"\u003cp\u003eFBXW5 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10013-20, BT-AP10013-50, BT-AP10013-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the F-box protein family| members of which are characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains| in addition to an F-box motif| so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene| however| they were found to be nonsense-mediated mRNA decay (NMD) candidates| hence not represented.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: FBXW5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: FBXW5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q969U6; Mouse: Q9QXW2; Rat: Q4KLI9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: FBXW5; F-box\/WD repeat-containing protein 5; F-box and WD-40 domain-containing protein 5)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 54461; Mouse: 30839; Rat: 362081\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238995386547,"sku":"BT-AP10013-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238995419315,"sku":"BT-AP10013-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238995452083,"sku":"BT-AP10013-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7db3c403-0b8e-448d-8f57-883c00f72f9f.png?v=1769387692","url":"https:\/\/afsbio.com\/products\/fbxw5-rabbit-polyclonal-antibody-bt-ap10013","provider":"AFSBio Inc.","version":"1.0","type":"link"}