{"product_id":"fbxw8-polyclonal-antibody-e-ab-17953","title":"FBXW8 Polyclonal Antibody - E-AB-17953","description":"\u003cp\u003eFBXW8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17953-60, E-AB-17953-120, E-AB-17953-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: FBXW8\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: F box and WD40 domain containing protein 8; F box only protein 29; F box\/WD repeat containing protein 8; F-box and WD-40 domain-containing protein 8; F-box only protein 29; F-box\/WD repeat-containing protein 8; FBW6; FBW8; FBX29; FBXO29; FBXW6; FBXW8; FBXW8\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q8N3Y1\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.92 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human FBXW8\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130664878259,"sku":"E-AB-17953-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130664911027,"sku":"E-AB-17953-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130664943795,"sku":"E-AB-17953-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f216b2fe-30ce-474c-a8eb-06d9e49fd7fc.png?v=1709811053","url":"https:\/\/afsbio.com\/products\/fbxw8-polyclonal-antibody-e-ab-17953","provider":"AFSBio Inc.","version":"1.0","type":"link"}