{"product_id":"fh-fumarase-mouse-mab-em1156","title":"FH\/Fumarase Mouse mAb - EM1156","description":"\u003cp\u003eFH\/Fumarase Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1156-50, EM1156-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Fumarase (FH) is an enzyme that catalyzes the reversible hydration\/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1, 000-3, 000 IF 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 50kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 2271\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P07954\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm,  Mitochondrion\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201990287539,"sku":"EM1156-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201990320307,"sku":"EM1156-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_08bd2714-7bce-4a13-9f07-1b68548f8329.png?v=1767119463","url":"https:\/\/afsbio.com\/products\/fh-fumarase-mouse-mab-em1156","provider":"AFSBio Inc.","version":"1.0","type":"link"}