{"product_id":"fhl3-polyclonal-antibody-bt-ap15587","title":"FHL3 Polyclonal Antibody - BT-AP15587","description":"\u003cp\u003eFHL3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15587-20, BT-AP15587-50, BT-AP15587-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Epigenetics and nuclear signaling; Tags and cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: FHL3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Four and a half LIM domains protein 3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13643; Mouse: Q9R059\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Four and a half LIM domains protein 3;FHL-3;Skeletal muscle LIM-protein 2;SLIM-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2275\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239139074227,"sku":"BT-AP15587-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239139106995,"sku":"BT-AP15587-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239139139763,"sku":"BT-AP15587-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_30e0d209-2aae-44bb-b282-9d2df183ff8c.png?v=1769389674","url":"https:\/\/afsbio.com\/products\/fhl3-polyclonal-antibody-bt-ap15587","provider":"AFSBio Inc.","version":"1.0","type":"link"}