{"product_id":"finetest®647-anti-human-cd328-siglec-7-antibody-fn25h-f647-30337","title":"FineTest®647 Anti-Human CD328\/Siglec-7 Antibody (FN25H) - F647-30337","description":"\u003cp\u003eFineTest®647 Anti-Human CD328\/Siglec-7 Antibody (FN25H)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20T, 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: F647-30337-20, F647-30337-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eTarget: Human CD328\u003c\/p\u003e\n\n\u003cp\u003eForm: Liquid\u003c\/p\u003e\n\n\u003cp\u003eConjugation: FineTest®647\u003c\/p\u003e\n\n\u003cp\u003eConjugation Information: FineTest® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660\/20 nm bandpass filter).\u003c\/p\u003e\n\n \n\n \n\n\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: FN25H\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eStorage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).\u003c\/p\u003e\n\n \n\n\u003cp\u003eSynonyms: Sialic acid-binding Ig-like lectin 7|Siglec-7|Adhesion inhibitory receptor molecule 1 (AIRM-1)|CDw328|D-siglec|QA79 membrane protein|p75|SIGLEC7|AIRM1|CD328\u003c\/p\u003e\n\n \n\n\u003cp\u003eUniprot ID: Q9Y286\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eTested Application: FC\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 27036\u003c\/p\u003e\n\n \n\n\u003cp\u003eResearch Area: Neuroscience, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eCategory: Flow cytometryometry Antibodies\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Fine Biotech","offers":[{"title":"20T","offer_id":45346381234355,"sku":"F647-30337-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100T","offer_id":45346381267123,"sku":"F647-30337-100","price":784.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/FineTest_Logo.png?v=1781809832","url":"https:\/\/afsbio.com\/products\/finetest%c2%ae647-anti-human-cd328-siglec-7-antibody-fn25h-f647-30337","provider":"AFSBio Inc.","version":"1.0","type":"link"}