{"product_id":"finetest®647-anti-mouse-cd279-pd-1-antibody-29f-1a12-f647-30018u","title":"FineTest®647 Anti-Mouse CD279\/PD-1 Antibody (29F.1A12) - F647-30018U","description":"\u003cp\u003eFineTest®647 Anti-Mouse CD279\/PD-1 Antibody (29F.1A12)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: F647-30018U-25, F647-30018U-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eTarget: Mouse CD279\/PD-1\u003c\/p\u003e\n\n\u003cp\u003eForm: Liquid\u003c\/p\u003e\n\n\u003cp\u003eConjugation: FineTest®647\u003c\/p\u003e\n\n\u003cp\u003eConjugation Information: FineTest® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660\/20 nm bandpass filter).\u003c\/p\u003e\n\n \n\n \n\n\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 29F.1A12\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG2a, κ\u003c\/p\u003e\n\n\u003cp\u003eStorage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.\u003c\/p\u003e\n\n \n\n\u003cp\u003eSynonyms: Programmed Death-1| PD-1\u003c\/p\u003e\n\n \n\n\u003cp\u003eUniprot ID: Q02242\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eTested Application: FC\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg\/10⁶ cells in 100 μL volume].\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 18566\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eCategory: Flow cytometryometry Antibodies\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Fine Biotech","offers":[{"title":"25μg","offer_id":45346358821043,"sku":"F647-30018U-25","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":45346358853811,"sku":"F647-30018U-100","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/FineTest_Logo.png?v=1781809832","url":"https:\/\/afsbio.com\/products\/finetest%c2%ae647-anti-mouse-cd279-pd-1-antibody-29f-1a12-f647-30018u","provider":"AFSBio Inc.","version":"1.0","type":"link"}