{"product_id":"finetest®647-anti-mouse-cd49b-pan-nk-cells-antibody-dx5-f647-30097u","title":"FineTest®647 Anti-Mouse CD49b\/pan-NK cells Antibody (DX5) - F647-30097U","description":"\u003cp\u003eFineTest®647 Anti-Mouse CD49b\/pan-NK cells Antibody (DX5)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: F647-30097U-25, F647-30097U-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eTarget: Mouse CD49b\/pan-NK cells\u003c\/p\u003e\n\n\u003cp\u003eForm: Liquid\u003c\/p\u003e\n\n\u003cp\u003eConjugation: FineTest®647\u003c\/p\u003e\n\n\u003cp\u003eConjugation Information: FineTest® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660\/20 nm bandpass filter).\u003c\/p\u003e\n\n \n\n \n\n\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: DX5\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgM, κ\u003c\/p\u003e\n\n\u003cp\u003eStorage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\n\u003cp\u003eBackground: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b\/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.\u003c\/p\u003e\n\n \n\n\u003cp\u003eSynonyms: CD49 antigen-like family member B| CD49b| Collagen receptor| GPIa| Integrin alpha-2| Platelet membrane glycoprotein Ia| VLA-2 subunit alpha| pan-NK cells\u003c\/p\u003e\n\n \n\n\u003cp\u003eUniprot ID: Q62469\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eTested Application: FC\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg\/10⁶ cells in 100 μL volume].\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 16398\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eCategory: Flow cytometryometry Antibodies\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Fine Biotech","offers":[{"title":"25μg","offer_id":45346356887731,"sku":"F647-30097U-25","price":238.0,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":45346356920499,"sku":"F647-30097U-100","price":602.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/FineTest_Logo.png?v=1781809832","url":"https:\/\/afsbio.com\/products\/finetest%c2%ae647-anti-mouse-cd49b-pan-nk-cells-antibody-dx5-f647-30097u","provider":"AFSBio Inc.","version":"1.0","type":"link"}