{"product_id":"finetest®700-anti-mouse-cd105-antibody-mj7-18-f700-30101","title":"FineTest®700 Anti-Mouse CD105 Antibody (MJ7\/18) - F700-30101","description":"\u003cp\u003eFineTest®700 Anti-Mouse CD105 Antibody (MJ7\/18)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50T, 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: F700-30101-50, F700-30101-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eTarget: Mouse CD105\u003c\/p\u003e\n\n\u003cp\u003eForm: Liquid\u003c\/p\u003e\n\n\u003cp\u003eConjugation: FineTest®700\u003c\/p\u003e\n\n\u003cp\u003eConjugation Information: FineTest® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725\/40 nm bandpass filter).\u003c\/p\u003e\n\n \n\n \n\n\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: MJ7\/18\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG2a, κ\u003c\/p\u003e\n\n\u003cp\u003eStorage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and\/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.\u003c\/p\u003e\n\n \n\n\u003cp\u003eSynonyms: END|Endoglin|Eng\u003c\/p\u003e\n\n \n\n\u003cp\u003eUniprot ID: Q63961\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eTested Application: FC\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 13805\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eCategory: Flow cytometryometry Antibodies\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Fine Biotech","offers":[{"title":"50T","offer_id":45346322841779,"sku":"F700-30101-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100T","offer_id":45346322874547,"sku":"F700-30101-100","price":700.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/FineTest_Logo.png?v=1781809832","url":"https:\/\/afsbio.com\/products\/finetest%c2%ae700-anti-mouse-cd105-antibody-mj7-18-f700-30101","provider":"AFSBio Inc.","version":"1.0","type":"link"}