{"product_id":"fitc-anti-mouse-il-17a-antibody-17f3-fitc-30267u","title":"FITC Anti-Mouse IL-17A Antibody (17F3) - FITC-30267U","description":"\u003cp\u003eFITC Anti-Mouse IL-17A Antibody (17F3)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: FITC-30267U-25, FITC-30267U-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eTarget: Mouse IL-17A\u003c\/p\u003e\n\n\u003cp\u003eForm: Liquid\u003c\/p\u003e\n\n\u003cp\u003eConjugation: FITC\u003c\/p\u003e\n\n\u003cp\u003eConjugation Information: FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525\/40 nm bandpass filter).\u003c\/p\u003e\n\n \n\n \n\n\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 17F3\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1, κ\u003c\/p\u003e\n\n\u003cp\u003eStorage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\n\u003cp\u003eBackground: The 17F3 Monoclonal Antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 Antibody has been shown to neutralize IL-36A in vivo.\u003c\/p\u003e\n\n \n\n\u003cp\u003eSynonyms: Ctla8| Il17a| Interleukin-17A\u003c\/p\u003e\n\n \n\n\u003cp\u003eUniprot ID: Q62386\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eTested Application: FC\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg\/10⁶ cells in 100 μL volume].\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 16171\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eCategory: Flow cytometryometry Antibodies\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Fine Biotech","offers":[{"title":"25μg","offer_id":45346370060467,"sku":"FITC-30267U-25","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":45346370093235,"sku":"FITC-30267U-100","price":378.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/FineTest_Logo.png?v=1781809832","url":"https:\/\/afsbio.com\/products\/fitc-anti-mouse-il-17a-antibody-17f3-fitc-30267u","provider":"AFSBio Inc.","version":"1.0","type":"link"}