{"product_id":"flk-1-flt-4-polyclonal-antibody-bt-ap03273","title":"Flk-1\/Flt-4 Polyclonal Antibody - BT-AP03273","description":"\u003cp\u003eFlk-1\/Flt-4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03273-20, BT-AP03273-50, BT-AP03273-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR encodes one of the two receptors of the VEGF.Kinase insert domain receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of KDR are implicated in infantile capillary hemangiomas.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KDR\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Flk-1\/Flt-4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 151527\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P35968\/P35916; Rat: O08775\/Q91ZT1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: KDR; FLK1; VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD antigen CD309; FL\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3791\/2324; Mouse: 14257; Rat: 25589\/114110\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240308727987,"sku":"BT-AP03273-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240308760755,"sku":"BT-AP03273-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240308793523,"sku":"BT-AP03273-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_00fc6517-f92f-4610-8798-51aeea6745b2.png?v=1769406575","url":"https:\/\/afsbio.com\/products\/flk-1-flt-4-polyclonal-antibody-bt-ap03273","provider":"AFSBio Inc.","version":"1.0","type":"link"}