{"product_id":"fndc5-monoclonal-antibody-mb67152","title":"FNDC5 Monoclonal Antibody-MB67152","description":"\u003cp\u003eFNDC5 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB67152-50, MB67152-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q8NAU1\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Fibronectins are multi-domain glycoproteins that bind to a variety of substances including collagen, Actin, heparin, DNA, fibrin and Fibronectin receptors. They are involved in a diverse array of important functions such as blood coagulation, wound healing, cell adhesion, cell differentiation and migration. FNDC5 (Fibronectin type III domain containing 5), also known as FRCP2, is a 196 amino acid single-pass type I membrane protein that is imported in peroxisomes through the Peroxin 5 receptor pathway. Existing as four alternatively spliced isoforms, FNDC5 is encoded by a gene located on human chromosome 1p35.1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: This antibody is purified through a protein G column.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of FNDC5 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of FNDC5 expression in human skeletal muscle (A) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 22 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: FRCP2; Fibronectin type III domain-containing protein 5; Fibronectin type III repeat-containing protein 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FNDC5. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906413170867,"sku":"MB67152-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906413203635,"sku":"MB67152-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_7b363428-569a-4a1a-9538-31fd856dfb52.jpg?v=1702919179","url":"https:\/\/afsbio.com\/products\/fndc5-monoclonal-antibody-mb67152","provider":"AFSBio Inc.","version":"1.0","type":"link"}