{"product_id":"foxa1-monoclonal-antibody-mb10931","title":"FOXA1 Monoclonal Antibody-MB10931","description":"\u003cp\u003eFOXA1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB10931-50, MB10931-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P55317\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Forkhead box protein A1 is a transcription factor required for the development of endoderm-derived organs, such as liver, lung, and prostate. FoxA1 functions as a pioneer factor that is recruited primarily to the distant enhancers to change chromatin structure for transcription in a cell type-specific manner. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 49 kDa; Observed MW: 49 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of FOXA1 in T47D lysates using FOXA1 antibody., Western blot analysis of FOXA1 in C6 lysates using FOXA1 antibody., Immunocytochemistry analysis of FOXA1 in MCF-7 using FOXA1 antibody, and DAPI\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: FOXA1; Forkhead box A1; Forkhead box protein A1; HNF-3-alpha; TCF3A; HNF3A; Transcription factor 3A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human FOXA1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43004735684787,"sku":"MB10931-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43004735717555,"sku":"MB10931-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_11bc2275-735a-40b8-8423-1b0cbba0d4e7.jpg?v=1706445033","url":"https:\/\/afsbio.com\/products\/foxa1-monoclonal-antibody-mb10931","provider":"AFSBio Inc.","version":"1.0","type":"link"}