{"product_id":"foxp2-monoclonal-antibody-bt-mca4745","title":"FOXP2 Monoclonal Antibody - BT-MCA4745","description":"\u003cp\u003eFOXP2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4745-50, BT-MCA4745-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the forkhead\/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: FOXP2\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5C11A8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: FOXP2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human MAPK3 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 85kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O15409\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SPCH1, CAGH44, TNRC10, DKFZp686H1726\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 93986\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238424961203,"sku":"BT-MCA4745-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238424993971,"sku":"BT-MCA4745-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ea45ee06-ff19-4d3a-ac95-990f0d8a2fd9.png?v=1769380579","url":"https:\/\/afsbio.com\/products\/foxp2-monoclonal-antibody-bt-mca4745","provider":"AFSBio Inc.","version":"1.0","type":"link"}